{
  "groups": {
    "nodes": [
      "Clinical",
      "Entity",
      "Evidence",
      "Functional",
      "Genetic",
      "Interaction",
      "Metadata",
      "Model",
      "Ontology",
      "Prioritisation",
      "Regulatory",
      "Safety"
    ],
    "edges": [
      "Aggregation",
      "Experimental",
      "Hierarchy",
      "Other",
      "Relation"
    ]
  },
  "nodes": [
    {
      "id": "Adverse_reaction",
      "group": "Safety",
      "count": 10274,
      "description": "Definition for ADVERSE_REACTION nodes: scans the adverse drug reaction parquet to emit MedDRA reaction terms (PT codes/names) representing clinical adverse events used by pharmacovigilance edges in the KG.",
      "properties": [
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "adverse_reaction::10048799",
          "indexed": false
        },
        {
          "property": "event",
          "type": "STRING",
          "example": "acute generalised exanthematous pustulosis",
          "indexed": true
        },
        {
          "property": "meddraCode",
          "type": "STRING",
          "example": "10048799",
          "indexed": false
        }
      ]
    },
    {
      "id": "Biosample",
      "group": "Model",
      "count": 35691,
      "description": "Definition for BIOSAMPLE nodes: represents biological samples (e.g., cell types, tissues) derived from the Biosample ontology/dataset, providing a standardized vocabulary for sample attribution in the KG.",
      "properties": [
        {
          "property": "synonyms",
          "type": "STRING",
          "example": "",
          "indexed": true
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "biosampleName",
          "type": "STRING",
          "example": "realizable entity",
          "indexed": true
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "BFO_0000017",
          "indexed": false
        }
      ]
    },
    {
      "id": "Cancer_biomarkers.Target_disease_association",
      "group": "Evidence",
      "count": 1301,
      "description": "Definition for TARGET_DISEASE_ASSOCIATION_CANCER_BIOMARKERS nodes: filters Evidence parquet to cancer_biomarkers to emit biomarker-driven associations. Cancer Biomarkers is a manually curated set of alterations (mutations, CNVs, expression changes) observed to predict drug response or resistance in specific cancers/tumor types. Curators review clinical/preclinical studies and score the evidence. Inference: biomarker alteration in tumor -> reported sensitivity/ resistance to a drug -> expert curation/score -> target tied to the cancer with confidence, score, and implicated drug. The KG captures this curated biomarker -> response chain, not generic co-occurrence.",
      "properties": [
        {
          "property": "score",
          "type": "FLOAT",
          "example": 1.0,
          "indexed": false
        },
        {
          "property": "confidence",
          "type": "STRING",
          "example": "Case report",
          "indexed": false
        },
        {
          "property": "diseaseFromSourceMappedId",
          "type": "STRING",
          "example": "EFO_0003060",
          "indexed": false
        },
        {
          "property": "drugFromSource",
          "type": "STRING",
          "example": "Egfr Inhibitor 1st Gens",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "cancer_biomarkers",
          "indexed": false
        },
        {
          "property": "biomarkerName",
          "type": "STRING",
          "example": "EGFR (D761Y)",
          "indexed": true
        },
        {
          "property": "diseaseFromSource",
          "type": "STRING",
          "example": "Non-small cell lung cancer",
          "indexed": true
        },
        {
          "property": "targetFromSourceId",
          "type": "STRING",
          "example": "EGFR",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "0010fb8e532bdb5d0072cc5db9991923f3c4b121",
          "indexed": false
        }
      ]
    },
    {
      "id": "Cancer_gene_census.Target_disease_association",
      "group": "Genetic",
      "count": 91572,
      "description": "Definition for TARGET_DISEASE_ASSOCIATION_CANCER_GENE_CENSUS nodes: filters Evidence parquet to cancer_gene_census (CGC) somatic driver calls. CGC experts review tumor sequencing and literature to declare genes as drivers in specific cancers. Each record is that curated call: disease mapping, target ID, variant effect, direction on trait, and resource/evidence scores. The inference chain is tumor sequencing \u2192 expert curation of driver status \u2192 driver gene linked to cancer in the KG.",
      "properties": [
        {
          "property": "score",
          "type": "FLOAT",
          "example": 1.0,
          "indexed": false
        },
        {
          "property": "directionOnTrait",
          "type": "STRING",
          "example": "risk",
          "indexed": false
        },
        {
          "property": "resourceScore",
          "type": "FLOAT",
          "example": 1.0,
          "indexed": false
        },
        {
          "property": "diseaseFromSourceMappedId",
          "type": "STRING",
          "example": "EFO_1000233",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "cancer_gene_census",
          "indexed": false
        },
        {
          "property": "studyId",
          "type": "STRING",
          "example": "419",
          "indexed": false
        },
        {
          "property": "targetFromSourceId",
          "type": "STRING",
          "example": "ENSG00000139687",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "0001d0ebb6bc16a6c5bf742d4bcae4294afe6608",
          "indexed": false
        }
      ]
    },
    {
      "id": "Cell_line",
      "group": "Model",
      "count": 771,
      "description": "Definition for CELL_LINE nodes: explodes CRISPR evidence cell line entries from the Evidence parquet (sourceId==crispr) to emit experimental cell lines with IDs and names used as assay contexts in the KG.",
      "properties": [
        {
          "property": "name",
          "type": "STRING",
          "example": "HCC70",
          "indexed": true
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "tissue",
          "type": "STRING",
          "example": "breast",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "SIDM00673",
          "indexed": false
        },
        {
          "property": "tissueId",
          "type": "STRING",
          "example": "UBERON_0000310",
          "indexed": false
        }
      ]
    },
    {
      "id": "Chembl.Target_disease_association",
      "group": "Clinical",
      "count": 569506,
      "description": "Definition for TARGET_DISEASE_ASSOCIATION_CHEMBL nodes: filters Evidence parquet to chembl known-drug clinical evidence. Each record is a clinical study/trial where a drug modulating this target was tested in a disease. It carries trial phase/status, cohort phenotypes, variant effect and direction on trait, disease IDs, study IDs/dates, and scores. Inference: drug hits target \u2192 trial in patients with the disease \u2192 observe outcome/phase and direction \u2192 encode as interventional evidence in the KG.",
      "properties": [
        {
          "property": "score",
          "type": "FLOAT",
          "example": 0.1,
          "indexed": false
        },
        {
          "property": "directionOnTrait",
          "type": "STRING",
          "example": "protect",
          "indexed": false
        },
        {
          "property": "clinicalPhase",
          "type": "FLOAT",
          "example": 1.0,
          "indexed": false
        },
        {
          "property": "diseaseFromSourceMappedId",
          "type": "STRING",
          "example": "MONDO_0002050",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "chembl",
          "indexed": false
        },
        {
          "property": "studyId",
          "type": "STRING",
          "example": "NCT03237286",
          "indexed": false
        },
        {
          "property": "studyStartDate",
          "type": "STRING",
          "example": "2017-12-01",
          "indexed": false
        },
        {
          "property": "diseaseFromSource",
          "type": "STRING",
          "example": "Depression",
          "indexed": true
        },
        {
          "property": "targetFromSourceId",
          "type": "STRING",
          "example": "Q05586",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "00009e083efc33e86e288352f5e9f619d233aee5",
          "indexed": false
        },
        {
          "property": "clinicalStatus",
          "type": "STRING",
          "example": "Completed",
          "indexed": false
        }
      ]
    },
    {
      "id": "Clingen.Target_disease_association",
      "group": "Clinical",
      "count": 3904,
      "description": "Definition for TARGET_DISEASE_ASSOCIATION_CLINGEN nodes: filters Evidence parquet to clingen curated clinical genetics. ClinGen experts review human genetic evidence and assign gene-disease validity with allelic requirements and confidence. Records retain disease IDs (source/mapped), study ID, score, target IDs, and allelic requirements. The logic is human variant observations \u2192 expert validity assessment \u2192 gene-disease assertion captured in the KG.",
      "properties": [
        {
          "property": "allelicRequirements",
          "type": "STRING",
          "example": "AD",
          "indexed": false
        },
        {
          "property": "diseaseFromSourceId",
          "type": "STRING",
          "example": "MONDO:0012526",
          "indexed": false
        },
        {
          "property": "score",
          "type": "FLOAT",
          "example": 1.0,
          "indexed": false
        },
        {
          "property": "confidence",
          "type": "STRING",
          "example": "Definitive",
          "indexed": false
        },
        {
          "property": "diseaseFromSourceMappedId",
          "type": "STRING",
          "example": "MONDO_0012526",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "clingen",
          "indexed": false
        },
        {
          "property": "studyId",
          "type": "STRING",
          "example": "Hemostasis/Thrombosis Gene Curation Expert Panel",
          "indexed": false
        },
        {
          "property": "diseaseFromSource",
          "type": "STRING",
          "example": "hereditary angioedema type 3",
          "indexed": true
        },
        {
          "property": "targetFromSourceId",
          "type": "STRING",
          "example": "F12",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "000efb50f8365a56ccc24e4026f7ed5eee25b916",
          "indexed": false
        }
      ]
    },
    {
      "id": "Colocalisation",
      "group": "Entity",
      "count": 215891664,
      "description": "Definition for COLOCALISATION nodes: represents a colocalisation event between two StudyLocus nodes.",
      "properties": [
        {
          "property": "colocalisationMethod",
          "type": "STRING",
          "example": "COLOC_PIP_ECAVIAR",
          "indexed": false
        },
        {
          "property": "numberColocalisingVariants",
          "type": "INTEGER",
          "example": 239,
          "indexed": false
        },
        {
          "property": "rightStudyType",
          "type": "STRING",
          "example": "gwas",
          "indexed": false
        },
        {
          "property": "clpp",
          "type": "FLOAT",
          "example": 0.003739942184214942,
          "indexed": false
        },
        {
          "property": "chromosome",
          "type": "STRING",
          "example": "7",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "h3",
          "type": "FLOAT",
          "example": 0.19421419660568473,
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "colocalisation::ec97b401f8d8f2db",
          "indexed": false
        },
        {
          "property": "h4",
          "type": "FLOAT",
          "example": 0.8057858033943154,
          "indexed": false
        }
      ]
    },
    {
      "id": "Credible_set",
      "group": "Entity",
      "count": 3484825,
      "description": "Definition for CREDIBLE_SET nodes: represents a set of candidate variants (credible set) fine-mapped from a StudyLocus, capturing method, confidence, and physical coordinates.",
      "properties": [
        {
          "property": "credibleSetIndex",
          "type": "INTEGER",
          "example": 1,
          "indexed": false
        },
        {
          "property": "pValueExponent",
          "type": "INTEGER",
          "example": -8,
          "indexed": false
        },
        {
          "property": "finemappingMethod",
          "type": "STRING",
          "example": "SuSie",
          "indexed": false
        },
        {
          "property": "credibleSetlog10BF",
          "type": "FLOAT",
          "example": 6.214039325714111,
          "indexed": false
        },
        {
          "property": "chromosome",
          "type": "STRING",
          "example": "1",
          "indexed": false
        },
        {
          "property": "confidence",
          "type": "STRING",
          "example": "SuSiE fine-mapped credible set with in-sample LD",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "position",
          "type": "INTEGER",
          "example": 14677,
          "indexed": false
        },
        {
          "property": "pValueMantissa",
          "type": "FLOAT",
          "example": 9.527000427246094,
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "e62f70cd4aa982aad471ba67e3915ec3",
          "indexed": false
        },
        {
          "property": "beta",
          "type": "FLOAT",
          "example": 1.17782,
          "indexed": false
        }
      ]
    },
    {
      "id": "Crispr.Target_disease_association",
      "group": "Functional",
      "count": 517,
      "description": "Definition for TARGET_DISEASE_ASSOCIATION_CRISPR nodes: filters Evidence parquet to crispr source to emit CRISPR functional screen associations. CRISPR perturbs genes in disease-relevant cell lines; if knocking out a gene changes a phenotype linked to the disease, the gene is implicated. Records keep disease IDs, target IDs/symbols, and resource/overall scores. The inference is perturb gene \u2192 observe phenotype change \u2192 link gene to disease in the KG.",
      "properties": [
        {
          "property": "score",
          "type": "FLOAT",
          "example": 0.415,
          "indexed": false
        },
        {
          "property": "resourceScore",
          "type": "FLOAT",
          "example": 36.560001373291016,
          "indexed": false
        },
        {
          "property": "diseaseFromSourceMappedId",
          "type": "STRING",
          "example": "EFO_0000305",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "crispr",
          "indexed": false
        },
        {
          "property": "diseaseFromSource",
          "type": "STRING",
          "example": "breast carcinoma",
          "indexed": true
        },
        {
          "property": "targetFromSourceId",
          "type": "STRING",
          "example": "ENSG00000127191",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "0028cb7aee04096c422dc7e592c360a4ef568c6c",
          "indexed": false
        },
        {
          "property": "diseaseCellLines",
          "type": "STRING",
          "example": "<open_targets.adapter.data_view.ArrayDataView object at 0x7fb51fa83190>",
          "indexed": false
        }
      ]
    },
    {
      "id": "Crispr_screen.Target_disease_association",
      "group": "Functional",
      "count": 21681,
      "description": "Definition for TARGET_DISEASE_ASSOCIATION_CRISPR_SCREEN nodes: filters Evidence parquet to crispr_screen source to emit detailed CRISPR screen results. Screens perturb genes across cell types/libraries; significant contrasts (log2FC) link a gene to a disease model. Records keep cell type, library, contrast, genetic background, log2FC, project/study metadata, and scores. Inference: perturb gene in disease-model cells \u2192 observe strong viability/phenotype shift \u2192 link gene to disease in the KG.",
      "properties": [
        {
          "property": "log2FoldChangeValue",
          "type": "FLOAT",
          "example": 2.69546780317798,
          "indexed": false
        },
        {
          "property": "crisprScreenLibrary",
          "type": "STRING",
          "example": "hCRISPRi_v2 H1 and H4",
          "indexed": false
        },
        {
          "property": "statisticalTestTail",
          "type": "STRING",
          "example": "upper tail",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "crispr_screen",
          "indexed": false
        },
        {
          "property": "score",
          "type": "FLOAT",
          "example": 0.7615818914544694,
          "indexed": false
        },
        {
          "property": "cellType",
          "type": "STRING",
          "example": "Astrocyte",
          "indexed": false
        },
        {
          "property": "resourceScore",
          "type": "FLOAT",
          "example": 0.014990158379077911,
          "indexed": false
        },
        {
          "property": "contrast",
          "type": "STRING",
          "example": "Lysosome exocytosis (cell-surface LAMP1 levels)",
          "indexed": false
        },
        {
          "property": "diseaseFromSourceMappedId",
          "type": "STRING",
          "example": "MONDO_0004975",
          "indexed": false
        },
        {
          "property": "studyId",
          "type": "STRING",
          "example": "iAstrocyte-LAMP1-Veh-CRISPRi",
          "indexed": false
        },
        {
          "property": "diseaseFromSource",
          "type": "STRING",
          "example": "neurodegenerative disease, lysosomal storage disease, AD, PD, MS",
          "indexed": false
        },
        {
          "property": "targetFromSourceId",
          "type": "STRING",
          "example": "XPO7",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "000f3789799163c35d3377be8ba575ace4a0fab1",
          "indexed": false
        },
        {
          "property": "projectId",
          "type": "STRING",
          "example": "crispr_brain",
          "indexed": false
        },
        {
          "property": "studyOverview",
          "type": "STRING",
          "example": "Description",
          "indexed": false
        }
      ]
    },
    {
      "id": "Database_cross_reference",
      "group": "Metadata",
      "count": 300209,
      "description": "Definition for DATABASE_CROSS_REFERENCE nodes (disease xrefs): explodes the scalar `dbXRefs` array from the diseases parquet, hashes each string under the `database_cross_reference` namespace for the primary ID, and stores the string as property `value` so DISEASE nodes can point to external ontology/DB IDs. Definition for DATABASE_CROSS_REFERENCE nodes (HPO xrefs): explodes `dbXRefs` from the HPO parquet, hashes each string under the `database_cross_reference` namespace for the primary ID, and stores the raw string as property `value` so PHENOTYPE/HPO nodes can expose external identifiers. Definition for DATABASE_CROSS_REFERENCE nodes (target xrefs): explodes `dbXrefs` from the Targets parquet, hashes each string under the `database_cross_reference` namespace for the primary ID, and writes the raw string to property `value` so TARGET nodes surface external gene identifiers.",
      "properties": [
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "database_cross_reference::b84512b5fd4db32b",
          "indexed": false
        },
        {
          "property": "value",
          "type": "STRING",
          "example": "MONDO:0000510",
          "indexed": false
        }
      ]
    },
    {
      "id": "Disease",
      "group": "Entity",
      "count": 46673,
      "description": "Definition for DISEASE nodes: scans the diseases parquet (EFO/MONDO-derived) to yield clinical/phenotype concepts with names, codes, descriptions, and therapeutic-area flags that anchor associations, indications, and ontology hierarchies in the KG.",
      "properties": [
        {
          "property": "code",
          "type": "STRING",
          "example": "http://purl.obolibrary.org/obo/MONDO_0018764",
          "indexed": false
        },
        {
          "property": "name",
          "type": "STRING",
          "example": "microcephalic primordial dwarfism due to RTTN deficiency",
          "indexed": true
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "description",
          "type": "STRING",
          "example": "Microcephalic primordial dwarfism due to RTTN deficiency is a rare, genetic, multiple congenital anomalies/dysmorphic syndrome characterized by primary microcephaly, profound short stature, moderate to severe intellectual disability, global developmental delay, craniofacial dysmorphism (e.g. sloping forehead, high and broad nasal bridge) and variable brain malformations, including simplified gyration, pachygyria, polymicrogyria, reduced sulcation, dysgenesis of corpus callosum and deformed ventricles. Renal anomalies, bilateral hearing loss, multiple joint contractures, severe failure to thrive and a sacral lesion cephalad to the gluteal crease have also been reported.",
          "indexed": true
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "MONDO_0018764",
          "indexed": false
        },
        {
          "property": "isTherapeuticArea",
          "type": "BOOLEAN",
          "example": false,
          "indexed": false
        }
      ]
    },
    {
      "id": "Disease_phenotype_association",
      "group": "Entity",
      "count": 189203,
      "description": "Definition for DISEASE_PHENOTYPE_ASSOCIATION nodes: explodes disease->HPO evidence from the DiseaseToPhenotype parquet to reify each association with mapped aspect, evidence type, frequency, sex, and curation metadata, providing traceable disease\u2013phenotype links in the KG.",
      "properties": [
        {
          "property": "aspect",
          "type": "STRING",
          "example": "Phenotypic abnormality",
          "indexed": false
        },
        {
          "property": "evidenceType",
          "type": "STRING",
          "example": "Traceable Author Statement",
          "indexed": false
        },
        {
          "property": "bioCuration",
          "type": "STRING",
          "example": "HPO:skoehler[2013-03-15]",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "5152cbe391b71011",
          "indexed": false
        }
      ]
    },
    {
      "id": "Disease_synonym",
      "group": "Metadata",
      "count": 118208,
      "description": "Definition for DISEASE_SYNONYM nodes (broad): explodes broad synonyms from the diseases parquet to emit synonym nodes keyed by namespaced hash, storing the synonym string for DISEASE synonym edges in the KG. Definition for DISEASE_SYNONYM nodes (exact): explodes exact synonyms from the diseases parquet to emit synonym nodes keyed by namespaced hash, storing the synonym string for DISEASE synonym edges in the KG. Definition for DISEASE_SYNONYM nodes (narrow): explodes narrow synonyms from the diseases parquet to emit synonym nodes keyed by namespaced hash, storing the synonym string for DISEASE synonym edges in the KG. Definition for DISEASE_SYNONYM nodes (related): explodes related synonyms from the diseases parquet to emit synonym nodes keyed by namespaced hash, storing the synonym string for DISEASE synonym edges in the KG.",
      "properties": [
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "disease_synonym::630b6285b420455a",
          "indexed": false
        },
        {
          "property": "value",
          "type": "STRING",
          "example": "energy pathways",
          "indexed": true
        }
      ]
    },
    {
      "id": "Drug_warning",
      "group": "Safety",
      "count": 2302,
      "description": "Definition for DRUG_WARNING nodes: scans ChEMBL drug warning records to emit warning entities (toxicity class, country, description, warning type, year), serving as safety annotations attached to molecules in the KG.",
      "properties": [
        {
          "property": "country",
          "type": "STRING",
          "example": "United States",
          "indexed": false
        },
        {
          "property": "warningType",
          "type": "STRING",
          "example": "Black Box Warning",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "toxicityClass",
          "type": "STRING",
          "example": "hepatotoxicity",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "drug_warning::1",
          "indexed": false
        }
      ]
    },
    {
      "id": "Europepmc.Target_disease_association",
      "group": "Clinical",
      "count": 23345129,
      "description": "Definition for TARGET_DISEASE_ASSOCIATION_EUROPEPMC nodes: filters Evidence parquet to europepmc text-mined literature evidence. Co-mentions of targets and diseases in publications are scored (resource score/overall score) and mapped to target/disease IDs. Inference: mine papers \u2192 detect target\u2013disease co-mention \u2192 assign relevance score \u2192 represent as literature-derived association in the KG.",
      "properties": [
        {
          "property": "literature",
          "type": "STRING",
          "example": "40126931",
          "indexed": false
        },
        {
          "property": "score",
          "type": "FLOAT",
          "example": 0.05,
          "indexed": false
        },
        {
          "property": "resourceScore",
          "type": "FLOAT",
          "example": 5.0,
          "indexed": false
        },
        {
          "property": "textMiningSentences",
          "type": "STRING",
          "example": "<open_targets.adapter.data_view.ArrayDataView object at 0x7fb1e6175420>",
          "indexed": false
        },
        {
          "property": "diseaseFromSourceMappedId",
          "type": "STRING",
          "example": "EFO_0000771",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "europepmc",
          "indexed": false
        },
        {
          "property": "targetFromSourceId",
          "type": "STRING",
          "example": "ENSG00000115263",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "00002b7d5b1af76b0ea2621d5143ae2e0806c1af",
          "indexed": false
        }
      ]
    },
    {
      "id": "Eva.Target_disease_association",
      "group": "Genetic",
      "count": 3535067,
      "description": "Definition for TARGET_DISEASE_ASSOCIATION_EVA nodes: filters Evidence parquet to eva germline submissions (ClinVar/EVA). ClinVar submitters assert whether a germline variant is pathogenic/benign for a disease. Each record keeps variant IDs (HGVS/RS), functional consequence, allele origin, allelic requirements, direction on trait, clinical significance, cohort phenotypes, and confidence/ score with disease/target IDs. Inference: clinical genetics lab submission \u2192 asserted variant pathogenicity \u2192 map to gene and disease \u2192 represent curated germline evidence in the KG.",
      "properties": [
        {
          "property": "confidence",
          "type": "STRING",
          "example": "criteria provided, single submitter",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "eva",
          "indexed": false
        },
        {
          "property": "variantFunctionalConsequenceId",
          "type": "STRING",
          "example": "SO_0001583",
          "indexed": false
        },
        {
          "property": "variantRsId",
          "type": "STRING",
          "example": "rs876660803",
          "indexed": false
        },
        {
          "property": "diseaseFromSourceId",
          "type": "STRING",
          "example": "C0677776",
          "indexed": false
        },
        {
          "property": "score",
          "type": "FLOAT",
          "example": 0.32,
          "indexed": false
        },
        {
          "property": "variantHgvsId",
          "type": "STRING",
          "example": "NC_000013.11:g.32394691C>A",
          "indexed": false
        },
        {
          "property": "diseaseFromSourceMappedId",
          "type": "STRING",
          "example": "MONDO_0003582",
          "indexed": false
        },
        {
          "property": "clinicalSignificances",
          "type": "STRING",
          "example": "uncertain significance",
          "indexed": false
        },
        {
          "property": "studyId",
          "type": "STRING",
          "example": "RCV001326010",
          "indexed": false
        },
        {
          "property": "diseaseFromSource",
          "type": "STRING",
          "example": "Hereditary breast ovarian cancer syndrome",
          "indexed": false
        },
        {
          "property": "targetFromSourceId",
          "type": "STRING",
          "example": "ENSG00000139618",
          "indexed": false
        },
        {
          "property": "variantId",
          "type": "STRING",
          "example": "13_32394691_C_A",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "57bc1c8c26b5a61b610cf5652500fbf36494396a",
          "indexed": false
        },
        {
          "property": "alleleOrigins",
          "type": "STRING",
          "example": "germline",
          "indexed": false
        }
      ]
    },
    {
      "id": "Eva_somatic.Target_disease_association",
      "group": "Genetic",
      "count": 9342,
      "description": "Definition for TARGET_DISEASE_ASSOCIATION_EVA_SOMATIC nodes: filters Evidence parquet to eva_somatic tumor submissions. Somatic submissions describe tumor- acquired variants and their clinical interpretation. Each record carries variant IDs (HGVS/RS), functional consequence, allele origins, allelic requirements, direction on trait, clinical significance, cohort phenotypes, and disease/target IDs with confidence/score. Inference: tumor sequencing \u2192 clinical interpretation of variant relevance \u2192 map to gene and cancer \u2192 represent curated somatic evidence in the KG.",
      "properties": [
        {
          "property": "confidence",
          "type": "STRING",
          "example": "no assertion criteria provided",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "eva_somatic",
          "indexed": false
        },
        {
          "property": "variantFunctionalConsequenceId",
          "type": "STRING",
          "example": "SO_0001627",
          "indexed": false
        },
        {
          "property": "variantRsId",
          "type": "STRING",
          "example": "rs1043934741",
          "indexed": false
        },
        {
          "property": "diseaseFromSourceId",
          "type": "STRING",
          "example": "CN078023",
          "indexed": false
        },
        {
          "property": "score",
          "type": "FLOAT",
          "example": 0.9,
          "indexed": false
        },
        {
          "property": "variantHgvsId",
          "type": "STRING",
          "example": "NC_000007.14:g.87713394C>T",
          "indexed": false
        },
        {
          "property": "diseaseFromSourceMappedId",
          "type": "STRING",
          "example": "EFO_0022041",
          "indexed": false
        },
        {
          "property": "clinicalSignificances",
          "type": "STRING",
          "example": "drug response",
          "indexed": false
        },
        {
          "property": "studyId",
          "type": "STRING",
          "example": "RCV001029213",
          "indexed": false
        },
        {
          "property": "diseaseFromSource",
          "type": "STRING",
          "example": "Tramadol response",
          "indexed": false
        },
        {
          "property": "targetFromSourceId",
          "type": "STRING",
          "example": "ENSG00000105784",
          "indexed": false
        },
        {
          "property": "variantId",
          "type": "STRING",
          "example": "7_87713394_C_T",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "0005aee0f03f4c40db0dd74913d4154018e20ce8",
          "indexed": false
        },
        {
          "property": "alleleOrigins",
          "type": "STRING",
          "example": "somatic",
          "indexed": false
        }
      ]
    },
    {
      "id": "Expression_atlas.Target_disease_association",
      "group": "Functional",
      "count": 237329,
      "description": "Definition for TARGET_DISEASE_ASSOCIATION_EXPRESSION_ATLAS nodes: filters Evidence parquet to expression_atlas differential expression evidence. Genes measured in case vs control biosamples yield contrasts (log2FC/value/percentile); significant differential expression in disease-relevant tissues links the gene to the disease. Records store biosamples, contrasts, log2FC/percentile, literature, study overview/ID, confidence/resource scores, and disease/target IDs. Inference: measure expression in disease vs baseline \u2192 observe differential expression \u2192 link gene to disease in the KG (note: expression evidence is not ontology-propagated).",
      "properties": [
        {
          "property": "biosamplesFromSource",
          "type": "STRING",
          "example": "UBERON_0002421",
          "indexed": false
        },
        {
          "property": "log2FoldChangeValue",
          "type": "FLOAT",
          "example": -1.2,
          "indexed": false
        },
        {
          "property": "log2FoldChangePercentileRank",
          "type": "INTEGER",
          "example": 95,
          "indexed": false
        },
        {
          "property": "confidence",
          "type": "STRING",
          "example": "medium",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "expression_atlas",
          "indexed": false
        },
        {
          "property": "literature",
          "type": "STRING",
          "example": "17077275|18332434",
          "indexed": false
        },
        {
          "property": "score",
          "type": "FLOAT",
          "example": 0.029604426058595677,
          "indexed": false
        },
        {
          "property": "resourceScore",
          "type": "FLOAT",
          "example": 0.00253,
          "indexed": false
        },
        {
          "property": "contrast",
          "type": "STRING",
          "example": "'Alzheimers disease' vs 'normal' in 'hippocampus'",
          "indexed": false
        },
        {
          "property": "diseaseFromSourceMappedId",
          "type": "STRING",
          "example": "MONDO_0004975",
          "indexed": false
        },
        {
          "property": "studyId",
          "type": "STRING",
          "example": "E-GEOD-5281",
          "indexed": false
        },
        {
          "property": "targetFromSourceId",
          "type": "STRING",
          "example": "ENSG00000141367",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "88185810987db0becba13d4222fbc867d10f1278",
          "indexed": false
        },
        {
          "property": "studyOverview",
          "type": "STRING",
          "example": "Microarray analysis of six brain areas from Alzheimers disease patients and normal individuals",
          "indexed": true
        }
      ]
    },
    {
      "id": "Gene2phenotype.Target_disease_association",
      "group": "Clinical",
      "count": 5062,
      "description": "Definition for TARGET_DISEASE_ASSOCIATION_GENE2PHENOTYPE nodes: filters Evidence parquet to gene2phenotype curated gene-disease assertions. Gene2Phenotype curators review human genetic evidence and specify allelic requirements, variant functional consequence, and direction on trait. Each record carries disease IDs, study ID, confidence, score, and target IDs. Inference: human variant observations \u2192 curator assessment of causal gene-disease link \u2192 recorded as a curated assertion in the KG.",
      "properties": [
        {
          "property": "allelicRequirements",
          "type": "STRING",
          "example": "biallelic_autosomal",
          "indexed": false
        },
        {
          "property": "literature",
          "type": "STRING",
          "example": "22444670|25714577|27431780",
          "indexed": false
        },
        {
          "property": "score",
          "type": "FLOAT",
          "example": 1.0,
          "indexed": false
        },
        {
          "property": "confidence",
          "type": "STRING",
          "example": "definitive",
          "indexed": false
        },
        {
          "property": "diseaseFromSourceMappedId",
          "type": "STRING",
          "example": "MONDO_0009105",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "gene2phenotype",
          "indexed": false
        },
        {
          "property": "studyId",
          "type": "STRING",
          "example": "DD",
          "indexed": false
        },
        {
          "property": "diseaseFromSource",
          "type": "STRING",
          "example": "trichohepatoenteric syndrome",
          "indexed": true
        },
        {
          "property": "targetFromSourceId",
          "type": "STRING",
          "example": "SKIC2",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "000b43b63c9f4dd7228416f5ac03603245aae06d",
          "indexed": false
        },
        {
          "property": "variantFunctionalConsequenceId",
          "type": "STRING",
          "example": "SO_0002317",
          "indexed": false
        }
      ]
    },
    {
      "id": "Gene_burden.Target_disease_association",
      "group": "Genetic",
      "count": 41264,
      "description": "Definition for TARGET_DISEASE_ASSOCIATION_GENE_BURDEN nodes: filters Evidence parquet to gene_burden source to emit rare-variant burden associations. Burden tests collapse many rare variants in a gene into a single burden score and test carriers vs non-carriers for disease/trait difference. Arrow logic: sequence rare variants -> collapse into burden score -> regress burden against phenotype -> significant beta/OR/p-value -> link gene to disease. Records store regression effects, p-values, ancestry/cohort info, allelic requirements, and study metadata. The KG captures these gene-wide rare-variant signals rather than single-variant hits.",
      "properties": [
        {
          "property": "ancestry",
          "type": "STRING",
          "example": "EUR",
          "indexed": false
        },
        {
          "property": "pValueExponent",
          "type": "INTEGER",
          "example": -28,
          "indexed": false
        },
        {
          "property": "ancestryId",
          "type": "STRING",
          "example": "HANCESTRO_0005",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "gene_burden",
          "indexed": false
        },
        {
          "property": "betaConfidenceIntervalLower",
          "type": "FLOAT",
          "example": 0.333,
          "indexed": false
        },
        {
          "property": "betaConfidenceIntervalUpper",
          "type": "FLOAT",
          "example": 0.475,
          "indexed": false
        },
        {
          "property": "literature",
          "type": "STRING",
          "example": "34662886",
          "indexed": false
        },
        {
          "property": "score",
          "type": "FLOAT",
          "example": 1.0,
          "indexed": false
        },
        {
          "property": "urls",
          "type": "STRING",
          "example": "<open_targets.adapter.data_view.ArrayDataView object at 0x7fb22a313e50>",
          "indexed": false
        },
        {
          "property": "statisticalMethodOverview",
          "type": "STRING",
          "example": "Burden test carried out with pLOF and deleterious missense variants with a MAF smaller than 0.001%.",
          "indexed": false
        },
        {
          "property": "statisticalMethod",
          "type": "STRING",
          "example": "ADD-WGR-FIRTH_M3.0001",
          "indexed": false
        },
        {
          "property": "resourceScore",
          "type": "FLOAT",
          "example": 1.11e-28,
          "indexed": false
        },
        {
          "property": "diseaseFromSourceMappedId",
          "type": "STRING",
          "example": "EFO_0004324",
          "indexed": false
        },
        {
          "property": "diseaseFromSource",
          "type": "STRING",
          "example": "Ankle spacing width (3143)",
          "indexed": false
        },
        {
          "property": "pValueMantissa",
          "type": "FLOAT",
          "example": 1.11,
          "indexed": false
        },
        {
          "property": "targetFromSourceId",
          "type": "STRING",
          "example": "SMAD6",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "c57a9d8749e4b2a71f971eee4c80c69e2de3228f",
          "indexed": false
        },
        {
          "property": "studySampleSize",
          "type": "INTEGER",
          "example": 246319,
          "indexed": false
        },
        {
          "property": "projectId",
          "type": "STRING",
          "example": "REGENERON",
          "indexed": false
        },
        {
          "property": "beta",
          "type": "FLOAT",
          "example": 0.404,
          "indexed": false
        }
      ]
    },
    {
      "id": "Genetic_association_study",
      "group": "Genetic",
      "count": 2001227,
      "description": "Definition for GENETIC_ASSOCIATION_STUDY nodes: represents scientific studies (e.g., GWAS, clinical trials) from the Study dataset, acting as central hubs for linking traits, diseases, and genetic associations in the KG.",
      "properties": [
        {
          "property": "hasSumstats",
          "type": "BOOLEAN",
          "example": false,
          "indexed": false
        },
        {
          "property": "traitFromSource",
          "type": "STRING",
          "example": "Autoimmune hyperthyroidism",
          "indexed": true
        },
        {
          "property": "nControls",
          "type": "INTEGER",
          "example": 370637,
          "indexed": false
        },
        {
          "property": "studyType",
          "type": "STRING",
          "example": "gwas",
          "indexed": false
        },
        {
          "property": "nCases",
          "type": "INTEGER",
          "example": 2469,
          "indexed": false
        },
        {
          "property": "initialSampleSize",
          "type": "STRING",
          "example": "500,348 (282,064 females and 218,284 males)",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "nSamples",
          "type": "INTEGER",
          "example": 373106,
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "FINNGEN_R12_AUTOIMMUNE_HYPERTHYROIDISM",
          "indexed": false
        },
        {
          "property": "projectId",
          "type": "STRING",
          "example": "FINNGEN_R12",
          "indexed": false
        },
        {
          "property": "pubmedId",
          "type": "STRING",
          "example": "36653562",
          "indexed": false
        }
      ]
    },
    {
      "id": "Genomics_england.Target_disease_association",
      "group": "Clinical",
      "count": 48545,
      "description": "Definition for TARGET_DISEASE_ASSOCIATION_GENOMICS_ENGLAND nodes: filters Evidence parquet to genomics_england PanelApp associations. PanelApp curators review clinical sequencing cases and decide whether a gene is implicated in a disease, noting allelic requirements, confidence level, and supporting phenotypes. Each record carries those curations, plus disease IDs, study overview/ID, score, and target IDs. Inference: clinical cases -> expert panel evaluation -> gene-disease assertion captured for use in the KG.",
      "properties": [
        {
          "property": "confidence",
          "type": "STRING",
          "example": "green",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "genomics_england",
          "indexed": false
        },
        {
          "property": "allelicRequirements",
          "type": "STRING",
          "example": "BIALLELIC, autosomal or pseudoautosomal",
          "indexed": false
        },
        {
          "property": "diseaseFromSourceId",
          "type": "STRING",
          "example": "OMIM:243700",
          "indexed": false
        },
        {
          "property": "literature",
          "type": "STRING",
          "example": "20004785|19776401|25724123|25627830",
          "indexed": false
        },
        {
          "property": "score",
          "type": "FLOAT",
          "example": 1.0,
          "indexed": false
        },
        {
          "property": "diseaseFromSourceMappedId",
          "type": "STRING",
          "example": "Orphanet_169446",
          "indexed": false
        },
        {
          "property": "studyId",
          "type": "STRING",
          "example": "111",
          "indexed": false
        },
        {
          "property": "diseaseFromSource",
          "type": "STRING",
          "example": "Hyper-IgE recurrent infection syndrome, autosomal recessive",
          "indexed": true
        },
        {
          "property": "targetFromSourceId",
          "type": "STRING",
          "example": "DOCK8",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "0003610920bac11598bb1aabdcc5d9f9c1f731b6",
          "indexed": false
        },
        {
          "property": "cohortPhenotypes",
          "type": "STRING",
          "example": "Hyper-IgE recurrent infection syndrome, autosomal recessive 243700|Combined immunodeficiency|Hyper-IgE recurrent infection syndrome, autosomal recessive|Hyper IgE syndrome (HIES)|Immunodeficiencies affecting cellular and humoral immunity|Low NK cells with poor function, eosinophilia, recurrent infections, cutaneous viral, fungal and staphylococcal infections, severe atopy, cancer diathesis|Hyper-IgE recurrent infection syndrome|impaired T cell function, Atopy, cutaneous viral infections",
          "indexed": false
        },
        {
          "property": "studyOverview",
          "type": "STRING",
          "example": "COVID-19 research",
          "indexed": true
        }
      ]
    },
    {
      "id": "Go_term",
      "group": "Ontology",
      "count": 48196,
      "description": "Definition for GO_TERM nodes: scans the GO parquet to emit Gene Ontology terms with IDs and names, providing functional annotation entities that targets and pathways can link to in the KG.",
      "properties": [
        {
          "property": "name",
          "type": "STRING",
          "example": "mitochondrion inheritance",
          "indexed": true
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "GO:0000001",
          "indexed": false
        }
      ]
    },
    {
      "id": "Gwas_credible_sets.Target_disease_association",
      "group": "Genetic",
      "count": 2976160,
      "description": "Definition for TARGET_DISEASE_ASSOCIATION_GWAS_CREDIBLE_SETS nodes.",
      "properties": [
        {
          "property": "literature",
          "type": "STRING",
          "example": "35213538",
          "indexed": false
        },
        {
          "property": "score",
          "type": "FLOAT",
          "example": 0.2672857642173767,
          "indexed": false
        },
        {
          "property": "targetId",
          "type": "STRING",
          "example": "ENSG00000118137",
          "indexed": false
        },
        {
          "property": "studyLocusId",
          "type": "STRING",
          "example": "eeac42b54cd0bdb6686cc15193560d2f",
          "indexed": false
        },
        {
          "property": "datasourceId",
          "type": "STRING",
          "example": "gwas_credible_sets",
          "indexed": false
        },
        {
          "property": "diseaseFromSourceMappedId",
          "type": "STRING",
          "example": "OBA_VT0005144",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "uniprot_literature",
          "indexed": false
        },
        {
          "property": "curationDate",
          "type": "STRING",
          "example": "2022-02-25",
          "indexed": false
        },
        {
          "property": "targetFromSourceId",
          "type": "STRING",
          "example": "ENSG00000118137",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "00012fa2687910b20be25da5a57c5215d1b0a2b6",
          "indexed": false
        },
        {
          "property": "datatypeId",
          "type": "STRING",
          "example": "genetic_association",
          "indexed": false
        }
      ]
    },
    {
      "id": "Impc.Target_disease_association",
      "group": "Functional",
      "count": 1563525,
      "description": "Definition for TARGET_DISEASE_ASSOCIATION_IMPC nodes: filters Evidence parquet to impc mouse model evidence. IMPC perturbs mouse genes, observes phenotypes, maps those phenotypes to human diseases, and then maps the mouse gene to the human ortholog. Records keep model IDs (Ensembl/MGI), variant effect, direction on trait, disease IDs, and scores. Inference: mouse knockout \u2192 observed mouse phenotype \u2192 mapped to human disease \u2192 mapped to human ortholog gene \u2192 stored as in vivo evidence in the KG.",
      "properties": [
        {
          "property": "targetId",
          "type": "STRING",
          "example": "ENSG00000198646",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "impc",
          "indexed": false
        },
        {
          "property": "biologicalModelAllelicComposition",
          "type": "STRING",
          "example": "Ncoa6<tm2Jxu>/Ncoa6<tm2Jxu>",
          "indexed": false
        },
        {
          "property": "diseaseFromSourceId",
          "type": "STRING",
          "example": "OMIM:144250",
          "indexed": false
        },
        {
          "property": "targetInModelMgiId",
          "type": "STRING",
          "example": "MGI:1929915",
          "indexed": false
        },
        {
          "property": "score",
          "type": "FLOAT",
          "example": 0.4733,
          "indexed": false
        },
        {
          "property": "targetInModel",
          "type": "STRING",
          "example": "Ncoa6",
          "indexed": false
        },
        {
          "property": "directionOnTrait",
          "type": "STRING",
          "example": "risk",
          "indexed": false
        },
        {
          "property": "biologicalModelGeneticBackground",
          "type": "STRING",
          "example": "involves: 129S6/SvEvTac * C57BL/6 * FVB/N",
          "indexed": false
        },
        {
          "property": "resourceScore",
          "type": "FLOAT",
          "example": 47.33,
          "indexed": false
        },
        {
          "property": "datasourceId",
          "type": "STRING",
          "example": "impc",
          "indexed": false
        },
        {
          "property": "diseaseFromSourceMappedId",
          "type": "STRING",
          "example": "Orphanet_79211",
          "indexed": false
        },
        {
          "property": "diseaseFromSource",
          "type": "STRING",
          "example": "Hyperlipidemia, Familial Combined, 3",
          "indexed": false
        },
        {
          "property": "targetFromSourceId",
          "type": "STRING",
          "example": "ENSG00000198646",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "2167b099b7508b509f98f46e948e456444951779",
          "indexed": false
        },
        {
          "property": "targetInModelEnsemblId",
          "type": "STRING",
          "example": "ENSMUSG00000038369",
          "indexed": false
        }
      ]
    },
    {
      "id": "Intogen.Target_disease_association",
      "group": "Functional",
      "count": 4223,
      "description": "Definition for TARGET_DISEASE_ASSOCIATION_INTOGEN nodes: filters Evidence parquet to intogen driver discovery results. IntOGen aggregates tumor sequencing studies and runs driver-calling methods to identify genes under positive selection in specific cancers. Records retain cohort IDs/descriptions, significant driver methods, direction on trait, variant effect, resource/score, and target/disease IDs. Inference: aggregate somatic mutations \u2192 apply driver detection \u2192 call gene as driver in a cancer \u2192 record as driver-based association in the KG.",
      "properties": [
        {
          "property": "cohortShortName",
          "type": "STRING",
          "example": "PCAWG_WGS_HEAD_SCC",
          "indexed": false
        },
        {
          "property": "cohortId",
          "type": "STRING",
          "example": "PCAWG_WGS_HEAD_SCC",
          "indexed": false
        },
        {
          "property": "score",
          "type": "FLOAT",
          "example": 0.3019691062817906,
          "indexed": false
        },
        {
          "property": "cohortDescription",
          "type": "STRING",
          "example": "Head and Neck Squamous Cell Carcinoma from PCAWG",
          "indexed": false
        },
        {
          "property": "directionOnTrait",
          "type": "STRING",
          "example": "risk",
          "indexed": false
        },
        {
          "property": "resourceScore",
          "type": "FLOAT",
          "example": 0.023788700830867,
          "indexed": false
        },
        {
          "property": "diseaseFromSourceMappedId",
          "type": "STRING",
          "example": "EFO_0000181",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "intogen",
          "indexed": false
        },
        {
          "property": "diseaseFromSource",
          "type": "STRING",
          "example": "Head and Neck Squamous Cell Carcinoma",
          "indexed": true
        },
        {
          "property": "significantDriverMethods",
          "type": "STRING",
          "example": "combination",
          "indexed": false
        },
        {
          "property": "targetFromSourceId",
          "type": "STRING",
          "example": "B2M",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "0013bba7e2af118a4fba8657754fab7bda380834",
          "indexed": false
        }
      ]
    },
    {
      "id": "Literature_entry",
      "group": "Metadata",
      "count": 20908358,
      "description": "Definition for LITERATURE_ENTRY nodes: scans the literature index parquet to emit publication nodes (PMID/PMCID/date) keyed by a hashed primary ID, serving as reified articles that can support associations or mention entities in the KG.",
      "properties": [
        {
          "property": "month",
          "type": "INTEGER",
          "example": 7,
          "indexed": false
        },
        {
          "property": "year",
          "type": "INTEGER",
          "example": 1976,
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "literature_entry::1000030",
          "indexed": false
        },
        {
          "property": "pmid",
          "type": "STRING",
          "example": "1000030",
          "indexed": false
        },
        {
          "property": "day",
          "type": "INTEGER",
          "example": 1,
          "indexed": false
        }
      ]
    },
    {
      "id": "Mechanism_of_action",
      "group": "Entity",
      "count": 1725,
      "description": "Definition for MECHANISM_OF_ACTION nodes: explodes Mechanism of Action records by chemblId to emit reified pharmacology entries (action type, mechanism text, target type/name) that link molecules to their biological targets and provenance in the KG.",
      "properties": [
        {
          "property": "actionType",
          "type": "STRING",
          "example": "ACTIVATOR",
          "indexed": false
        },
        {
          "property": "targetName",
          "type": "STRING",
          "example": "AMP-activated protein kinase, AMPK",
          "indexed": true
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "targetType",
          "type": "STRING",
          "example": "protein complex group",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "d6336a37042bd76f",
          "indexed": false
        },
        {
          "property": "mechanismOfAction",
          "type": "STRING",
          "example": "AMP-activated protein kinase, AMPK activator",
          "indexed": true
        }
      ]
    },
    {
      "id": "Molecule",
      "group": "Entity",
      "count": 18475,
      "description": "Definition for MOLECULE nodes: scans the Molecule parquet (ChEMBL subset) to emit drug entities with modality, approval/withdrawn status, trade names, synonyms, description, max clinical phase, and structure IDs as the drug anchor for indications, mechanisms of action, warnings, and ADR edges in the KG.",
      "properties": [
        {
          "property": "tradeNames",
          "type": "STRING",
          "example": "",
          "indexed": false
        },
        {
          "property": "hasBeenWithdrawn",
          "type": "BOOLEAN",
          "example": false,
          "indexed": false
        },
        {
          "property": "inchiKey",
          "type": "STRING",
          "example": "LBJVBJYMZKEREY-UHFFFAOYSA-N",
          "indexed": false
        },
        {
          "property": "blackBoxWarning",
          "type": "BOOLEAN",
          "example": false,
          "indexed": false
        },
        {
          "property": "synonyms",
          "type": "STRING",
          "example": "ABI-H0731|Abi-h0731|Vebicorvir",
          "indexed": true
        },
        {
          "property": "name",
          "type": "STRING",
          "example": "VEBICORVIR",
          "indexed": true
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "description",
          "type": "STRING",
          "example": "Small molecule drug with a maximum clinical trial phase of II (across all indications) and has 2 investigational indications.",
          "indexed": true
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "CHEMBL4650324",
          "indexed": false
        },
        {
          "property": "drugType",
          "type": "STRING",
          "example": "Small molecule",
          "indexed": false
        },
        {
          "property": "maximumClinicalTrialPhase",
          "type": "FLOAT",
          "example": 2.0,
          "indexed": false
        },
        {
          "property": "isApproved",
          "type": "BOOLEAN",
          "example": false,
          "indexed": false
        }
      ]
    },
    {
      "id": "Mouse_gene",
      "group": "Model",
      "count": 12318,
      "description": "Definition for MOUSE_GENE nodes: scans Mouse Phenotypes parquet to emit mouse genes (Ensembl/MGI IDs, symbol) used in model annotations, anchoring mouse orthologs that link targets to in vivo evidence in the KG.",
      "properties": [
        {
          "property": "targetInModelMgiId",
          "type": "STRING",
          "example": "MGI:1914181",
          "indexed": false
        },
        {
          "property": "targetInModel",
          "type": "STRING",
          "example": "1700010I14Rik",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "ENSMUSG00000023873",
          "indexed": false
        }
      ]
    },
    {
      "id": "Mouse_phenotype",
      "group": "Model",
      "count": 10451,
      "description": "Definition for MOUSE_PHENOTYPE nodes: scans Mouse Phenotypes parquet to emit mouse phenotype terms (modelPhenotypeId/label) that mouse models and inference edges can point to, capturing in vivo phenotype observations in the KG.",
      "properties": [
        {
          "property": "modelPhenotypeLabel",
          "type": "STRING",
          "example": "decreased sperm progressive motility",
          "indexed": true
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "MP:0020451",
          "indexed": false
        }
      ]
    },
    {
      "id": "Mouse_phenotype_class",
      "group": "Model",
      "count": 9,
      "description": "Definition for MOUSE_PHENOTYPE_CLASS nodes: explodes phenotype class entries from the Mouse Phenotypes parquet to emit MP class terms (id/label) used to classify mouse phenotypes.",
      "properties": [
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "label",
          "type": "STRING",
          "example": "liver/biliary system phenotype",
          "indexed": true
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "MP:0005370",
          "indexed": false
        }
      ]
    },
    {
      "id": "Orphanet.Target_disease_association",
      "group": "Clinical",
      "count": 7189,
      "description": "Definition for TARGET_DISEASE_ASSOCIATION_ORPHANET nodes: filters Evidence parquet to orphanet rare-disease curation. Orphanet experts review clinical genetics for rare diseases and assert gene-disease links, noting allele origins, allelic requirements, direction on trait, and functional consequence. Records keep disease/target IDs, confidence, and scores. Inference: rare disease cases -> expert curation of causal gene -> recorded as curated rare-disease evidence in the KG.",
      "properties": [
        {
          "property": "diseaseFromSourceId",
          "type": "STRING",
          "example": "Orphanet_544472",
          "indexed": false
        },
        {
          "property": "score",
          "type": "FLOAT",
          "example": 1.0,
          "indexed": false
        },
        {
          "property": "directionOnTrait",
          "type": "STRING",
          "example": "risk",
          "indexed": false
        },
        {
          "property": "confidence",
          "type": "STRING",
          "example": "Assessed",
          "indexed": false
        },
        {
          "property": "diseaseFromSourceMappedId",
          "type": "STRING",
          "example": "MONDO_0035290",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "orphanet",
          "indexed": false
        },
        {
          "property": "diseaseFromSource",
          "type": "STRING",
          "example": "Atypical hemolytic uremic syndrome with complement gene abnormality",
          "indexed": true
        },
        {
          "property": "targetFromSourceId",
          "type": "STRING",
          "example": "ENSG00000243649",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "0002c0c29f868e9e2b459edf87ff65871ee61e39",
          "indexed": false
        },
        {
          "property": "alleleOrigins",
          "type": "STRING",
          "example": "germline|somatic",
          "indexed": false
        }
      ]
    },
    {
      "id": "Pathway",
      "group": "Ontology",
      "count": 2825,
      "description": "Definition for PATHWAY nodes: scans the Reactome parquet to emit pathway terms with IDs and labels, forming the pathway hierarchy and annotation targets for proteins/associations in the KG.",
      "properties": [
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "label",
          "type": "STRING",
          "example": "2-LTR circle formation",
          "indexed": true
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "R-HSA-164843",
          "indexed": false
        }
      ]
    },
    {
      "id": "Pharmacogenomics_annotation",
      "group": "Safety",
      "count": 5191,
      "description": "Definition for PHARMACOGENOMICS_ANNOTATION nodes: scans the pharmacogenomics parquet to emit clinical annotation records linking genetic variants to drug responses, carrying genotype, evidence level, directionality, phenotype text, PGx category, haplotype, and functional consequence details as the pharmacogenomics annotation nodes in the KG.",
      "properties": [
        {
          "property": "genotypeId",
          "type": "STRING",
          "example": "10_108778076_C_T,T",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "genotypeAnnotationText",
          "type": "STRING",
          "example": "Patients with the TT genotype may be at a decreased risk of developing alcoholism as compared to patients with the CC genotype. Other genetic and clinical factors may also affect a patient's risk of developing alcoholism.",
          "indexed": true
        },
        {
          "property": "isDirectTarget",
          "type": "BOOLEAN",
          "example": false,
          "indexed": false
        },
        {
          "property": "datatypeId",
          "type": "STRING",
          "example": "clinical_annotation",
          "indexed": false
        },
        {
          "property": "genotype",
          "type": "STRING",
          "example": "TT",
          "indexed": false
        },
        {
          "property": "variantRsId",
          "type": "STRING",
          "example": "rs56722963",
          "indexed": false
        },
        {
          "property": "pgxCategory",
          "type": "STRING",
          "example": "toxicity",
          "indexed": false
        },
        {
          "property": "phenotypeText",
          "type": "STRING",
          "example": "decreased risk of developing alcoholism",
          "indexed": true
        },
        {
          "property": "datasourceId",
          "type": "STRING",
          "example": "clinpgx",
          "indexed": false
        },
        {
          "property": "variantId",
          "type": "STRING",
          "example": "10_108778076_C_T",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "pharmacogenomics_annotation::1451151478",
          "indexed": false
        },
        {
          "property": "datasourceVersion",
          "type": "STRING",
          "example": "2025-10-05",
          "indexed": false
        },
        {
          "property": "evidenceLevel",
          "type": "STRING",
          "example": "3",
          "indexed": false
        }
      ]
    },
    {
      "id": "Phenotype",
      "group": "Entity",
      "count": 18452,
      "description": "Definition for PHENOTYPE nodes: scans the HPO parquet to emit phenotype terms with IDs, names, and descriptions, anchoring clinical signs/symptoms for disease associations and mouse mapping in the KG.",
      "properties": [
        {
          "property": "name",
          "type": "STRING",
          "example": "2-hydroxyglutarate(2-)",
          "indexed": true
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "description",
          "type": "STRING",
          "example": "A dicarboxylic acid dianion resulting from the removal of a proton from both of the carboxylic acid groups of 2-hydroxyglutaric acid.",
          "indexed": true
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "CHEBI_11596",
          "indexed": false
        }
      ]
    },
    {
      "id": "Reactome.Target_disease_association",
      "group": "Clinical",
      "count": 10211,
      "description": "Definition for TARGET_DISEASE_ASSOCIATION_REACTOME nodes: filters Evidence parquet to reactome pathway-based inference. Reactome links proteins to pathway steps and curates disease annotations for those pathways. If a target is involved in a disease-annotated pathway, it is linked to the disease with modulation and score. Records include target modulation, variant amino acid descriptions, and disease/target IDs. Inference: target participates in pathway \u2192 pathway annotated to disease \u2192 target inherits disease link (pathway-level inference, not direct genetic/clinical evidence).",
      "properties": [
        {
          "property": "diseaseFromSourceId",
          "type": "STRING",
          "example": "DOID:9111",
          "indexed": false
        },
        {
          "property": "score",
          "type": "FLOAT",
          "example": 1.0,
          "indexed": false
        },
        {
          "property": "targetModulation",
          "type": "STRING",
          "example": "up_or_down",
          "indexed": false
        },
        {
          "property": "datasourceId",
          "type": "STRING",
          "example": "reactome",
          "indexed": false
        },
        {
          "property": "diseaseFromSourceMappedId",
          "type": "STRING",
          "example": "EFO_0005046",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "progeny",
          "indexed": false
        },
        {
          "property": "diseaseFromSource",
          "type": "STRING",
          "example": "cutaneous leishmaniasis",
          "indexed": true
        },
        {
          "property": "targetFromSourceId",
          "type": "STRING",
          "example": "Q9UKX2",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "007c741db91df1d9e8759305435cfec8ad5226e7",
          "indexed": false
        }
      ]
    },
    {
      "id": "Regulatory_element",
      "group": "Regulatory",
      "count": 48837502,
      "description": "Definition for REGULATORY_ELEMENT nodes: scans the enhancer_to_gene parquet to emit genomic regulatory regions (enhancers, promoters) with their genomic coordinates, type, score, and associated metadata.",
      "properties": [
        {
          "property": "distanceToTss",
          "type": "INTEGER",
          "example": 48534,
          "indexed": false
        },
        {
          "property": "score",
          "type": "FLOAT",
          "example": 0.6529697628007456,
          "indexed": false
        },
        {
          "property": "intervalType",
          "type": "STRING",
          "example": "intergenic",
          "indexed": false
        },
        {
          "property": "chromosome",
          "type": "STRING",
          "example": "1",
          "indexed": false
        },
        {
          "property": "start",
          "type": "INTEGER",
          "example": 778488,
          "indexed": false
        },
        {
          "property": "datasourceId",
          "type": "STRING",
          "example": "E2G",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "end",
          "type": "INTEGER",
          "example": 778988,
          "indexed": false
        },
        {
          "property": "studyId",
          "type": "STRING",
          "example": "ENCFF129GLS",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "0ffb8953c272b38cc6cb019fdb68eee3704f2814",
          "indexed": false
        }
      ]
    },
    {
      "id": "Species",
      "group": "Entity",
      "count": 13,
      "description": "Definition for SPECIES nodes: explodes homologue entries from the Targets parquet to emit species (id/name) nodes used in homology edges from human targets to other species in the KG.",
      "properties": [
        {
          "property": "speciesName",
          "type": "STRING",
          "example": "Human",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "speciesId",
          "type": "STRING",
          "example": "9606",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "species::9606",
          "indexed": false
        }
      ]
    },
    {
      "id": "Subcellular_location",
      "group": "Ontology",
      "count": 861,
      "description": "Definition for SUBCELLULAR_LOCATION nodes: scans UniProt subcellular location parquet to emit localization terms (labelSL/location/termSL) that targets can link to for cellular compartment context in the KG.",
      "properties": [
        {
          "property": "termSL",
          "type": "STRING",
          "example": "SL-0086",
          "indexed": false
        },
        {
          "property": "labelSL",
          "type": "STRING",
          "example": "Cellular component",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "location",
          "type": "STRING",
          "example": "Cytoplasm",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "subcellular_location::Cytoplasm",
          "indexed": false
        }
      ]
    },
    {
      "id": "Target",
      "group": "Entity",
      "count": 78725,
      "description": "Definition for TARGET nodes: scans the Targets parquet to emit Ensembl gene targets with symbol, name, biotype, and function descriptions as the core target entities used across drug, association, and annotation edges in the KG.",
      "properties": [
        {
          "property": "biotype",
          "type": "STRING",
          "example": "lncRNA",
          "indexed": false
        },
        {
          "property": "approvedName",
          "type": "STRING",
          "example": "novel transcript",
          "indexed": true
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "ENSG00000305987",
          "indexed": false
        },
        {
          "property": "approvedSymbol",
          "type": "STRING",
          "example": "ENSG00000305987",
          "indexed": true
        }
      ]
    },
    {
      "id": "Target_classification",
      "group": "Metadata",
      "count": 720,
      "description": "Definition for TARGET_CLASSIFICATION nodes: explodes target_class entries from the Targets parquet to emit classification terms (label/level) that group targets for categorization and navigation in the KG.",
      "properties": [
        {
          "property": "level",
          "type": "STRING",
          "example": "l1",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "label",
          "type": "STRING",
          "example": "Enzyme",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "target_classification::Enzyme",
          "indexed": false
        }
      ]
    },
    {
      "id": "Target_prioritisation",
      "group": "Prioritisation",
      "count": 78725,
      "description": "Definition for TARGET_PRIORITISATION nodes: scans the target_prioritisation parquet to emit target-specific scoring records from the Target Engine project, carrying tractability flags (hasPocket, hasLigand, isInMembrane, isSecreted), safety signals (hasSafetyEvent, geneticConstraint), development status (maxClinicalTrialPhase), and other druggability and conservation metrics as prioritisation evidence in the KG.",
      "properties": [
        {
          "property": "hasSmallMoleculeBinder",
          "type": "INTEGER",
          "example": 1,
          "indexed": false
        },
        {
          "property": "mouseOrthologMaxIdentityPercentage",
          "type": "FLOAT",
          "example": 0.19659499999999994,
          "indexed": false
        },
        {
          "property": "isSecreted",
          "type": "INTEGER",
          "example": 0,
          "indexed": false
        },
        {
          "property": "geneticConstraint",
          "type": "FLOAT",
          "example": -0.6249310535024821,
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "tissueDistribution",
          "type": "FLOAT",
          "example": 0.0,
          "indexed": false
        },
        {
          "property": "hasPocket",
          "type": "INTEGER",
          "example": 0,
          "indexed": false
        },
        {
          "property": "tissueSpecificity",
          "type": "FLOAT",
          "example": 0.75,
          "indexed": false
        },
        {
          "property": "hasLigand",
          "type": "INTEGER",
          "example": 1,
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "target_prioritisation::ENSG00000000938",
          "indexed": false
        },
        {
          "property": "maxClinicalTrialPhase",
          "type": "FLOAT",
          "example": 1.0,
          "indexed": false
        },
        {
          "property": "paralogMaxIdentityPercentage",
          "type": "FLOAT",
          "example": -0.2911149999999999,
          "indexed": false
        },
        {
          "property": "mouseKOScore",
          "type": "FLOAT",
          "example": -0.46968581511293017,
          "indexed": false
        },
        {
          "property": "isInMembrane",
          "type": "INTEGER",
          "example": 1,
          "indexed": false
        }
      ]
    },
    {
      "id": "Target_target_interaction",
      "group": "Interaction",
      "count": 11754722,
      "description": "Definition for TARGET_TARGET_INTERACTION nodes: scans interaction evidence parquet (STRING/IntAct-like) to emit reified interaction records with methods, scores, participant roles/sources, host organism/tissue, and detection details, serving as interaction evidence nodes linked to targets in the KG.",
      "properties": [
        {
          "property": "intB",
          "type": "STRING",
          "example": "ENSP00000272298",
          "indexed": false
        },
        {
          "property": "intA",
          "type": "STRING",
          "example": "ENSP00000000233",
          "indexed": false
        },
        {
          "property": "intASource",
          "type": "STRING",
          "example": "ensembl_protein",
          "indexed": false
        },
        {
          "property": "intBBiologicalRole",
          "type": "STRING",
          "example": "unspecified role",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "intABiologicalRole",
          "type": "STRING",
          "example": "unspecified role",
          "indexed": false
        },
        {
          "property": "interactionDetectionMethodMiIdentifier",
          "type": "STRING",
          "example": "MI:0110",
          "indexed": false
        },
        {
          "property": "interactionDetectionMethodShortName",
          "type": "STRING",
          "example": "textmining",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "20efce7224d0ef72",
          "indexed": false
        },
        {
          "property": "interactionScore",
          "type": "FLOAT",
          "example": 0.49,
          "indexed": false
        },
        {
          "property": "evidenceScore",
          "type": "FLOAT",
          "example": 0.125,
          "indexed": false
        },
        {
          "property": "intBSource",
          "type": "STRING",
          "example": "ensembl_protein",
          "indexed": false
        }
      ]
    },
    {
      "id": "Uniprot_literature.Target_disease_association",
      "group": "Clinical",
      "count": 6735,
      "description": "Definition for TARGET_DISEASE_ASSOCIATION_UNIPROT_LITERATURE nodes: filters Evidence parquet to uniprot_literature curated assertions. UniProt curators read the literature and annotate when a protein is implicated in a disease, noting target modulation and confidence. Records keep disease/target IDs and scores. Inference: manual literature curation \u2192 curator asserts protein\u2013disease link \u2192 captured as curated literature evidence in the KG.",
      "properties": [
        {
          "property": "diseaseFromSourceId",
          "type": "STRING",
          "example": "OMIM:618476",
          "indexed": false
        },
        {
          "property": "score",
          "type": "FLOAT",
          "example": 1.0,
          "indexed": false
        },
        {
          "property": "targetModulation",
          "type": "STRING",
          "example": "up_or_down",
          "indexed": false
        },
        {
          "property": "confidence",
          "type": "STRING",
          "example": "high",
          "indexed": false
        },
        {
          "property": "datasourceId",
          "type": "STRING",
          "example": "uniprot_literature",
          "indexed": false
        },
        {
          "property": "diseaseFromSourceMappedId",
          "type": "STRING",
          "example": "EFO_0010268",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "reactome",
          "indexed": false
        },
        {
          "property": "diseaseFromSource",
          "type": "STRING",
          "example": "Brain abnormalities, neurodegeneration, and dysosteosclerosis",
          "indexed": true
        },
        {
          "property": "targetFromSourceId",
          "type": "STRING",
          "example": "P07333",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "00196e43f13a0a514a79c9a1acb0f0fedf91e439",
          "indexed": false
        }
      ]
    },
    {
      "id": "Uniprot_variants.Target_disease_association",
      "group": "Clinical",
      "count": 36870,
      "description": "Definition for TARGET_DISEASE_ASSOCIATION_UNIPROT_VARIANTS nodes: filters Evidence parquet to uniprot_variants curated variant assertions. UniProt curators review literature and databases for protein variants linked to disease, capturing variant IDs (RS/id), functional consequence, target modulation, confidence, and scores. Inference: manual variant curation \u2192 variant tied to protein and disease \u2192 stored as curated variant evidence in the KG.",
      "properties": [
        {
          "property": "diseaseFromSourceId",
          "type": "STRING",
          "example": "OMIM:615512",
          "indexed": false
        },
        {
          "property": "score",
          "type": "FLOAT",
          "example": 1.0,
          "indexed": false
        },
        {
          "property": "targetModulation",
          "type": "STRING",
          "example": "up_or_down",
          "indexed": false
        },
        {
          "property": "confidence",
          "type": "STRING",
          "example": "high",
          "indexed": false
        },
        {
          "property": "datasourceId",
          "type": "STRING",
          "example": "uniprot_variants",
          "indexed": false
        },
        {
          "property": "diseaseFromSourceMappedId",
          "type": "STRING",
          "example": "MONDO_0014221",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "slapenrich",
          "indexed": false
        },
        {
          "property": "diseaseFromSource",
          "type": "STRING",
          "example": "Triosephosphate isomerase deficiency",
          "indexed": true
        },
        {
          "property": "targetFromSourceId",
          "type": "STRING",
          "example": "P60174",
          "indexed": false
        },
        {
          "property": "variantId",
          "type": "STRING",
          "example": "12_6870327_G_A",
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "0005e9f647616f5d3132c64643dc2e3c66f8f2e1",
          "indexed": false
        },
        {
          "property": "variantRsId",
          "type": "STRING",
          "example": "rs1555132614",
          "indexed": false
        }
      ]
    },
    {
      "id": "Variant",
      "group": "Entity",
      "count": 7136436,
      "description": "Definition for VARIANT nodes: represents genetic variants (e.g., SNPs, indels) identified by their unique ID, enabling the mapping of genotype-phenotype associations in the KG.",
      "properties": [
        {
          "property": "chromosome",
          "type": "STRING",
          "example": "1",
          "indexed": false
        },
        {
          "property": "preferred_id",
          "type": "STRING",
          "example": "id",
          "indexed": false
        },
        {
          "property": "referenceAllele",
          "type": "STRING",
          "example": "G",
          "indexed": false
        },
        {
          "property": "position",
          "type": "INTEGER",
          "example": 14677,
          "indexed": false
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "1_14677_G_A",
          "indexed": false
        },
        {
          "property": "alternateAllele",
          "type": "STRING",
          "example": "A",
          "indexed": false
        }
      ]
    }
  ],
  "links": [
    {
      "source": "Colocalisation",
      "target": "Credible_set",
      "label": "Compares_signal",
      "group": "Experimental",
      "count": 431783328,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "adab0799-5db5-4baa-a5d0-0ba26eb49eba"
        }
      ]
    },
    {
      "source": "Credible_set",
      "target": "Variant",
      "label": "Contains_variant",
      "group": "Experimental",
      "count": 88924954,
      "properties": [
        {
          "property": "standardError",
          "type": "FLOAT",
          "example": 0.212414
        },
        {
          "property": "pValueExponent",
          "type": "INTEGER",
          "example": -8
        },
        {
          "property": "posteriorProbability",
          "type": "FLOAT",
          "example": 0.95000001
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "c6e9ee9a-41ff-439c-9d63-20b68cc2843e"
        },
        {
          "property": "pValueMantissa",
          "type": "FLOAT",
          "example": 9.527000427246094
        },
        {
          "property": "logBF",
          "type": "FLOAT",
          "example": 14.3083546469727
        },
        {
          "property": "beta",
          "type": "FLOAT",
          "example": 1.17782
        }
      ]
    },
    {
      "source": "Regulatory_element",
      "target": "Biosample",
      "label": "Active_in",
      "group": "Hierarchy",
      "count": 48854316,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "808ba2f6-1886-4ef5-8526-24ad1bfc6b58"
        }
      ]
    },
    {
      "source": "Regulatory_element",
      "target": "Target",
      "label": "Regulates",
      "group": "Experimental",
      "count": 48852517,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "d382b806-22c0-4080-b7c1-5a3d7bf17677"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Target_target_interaction",
      "label": "Has_target_target_interaction",
      "group": "Relation",
      "count": 45011526,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "a21bd96e-4d4a-4194-9582-f494d11bd82d"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Europepmc.Target_disease_association",
      "label": "Subject_of",
      "group": "Other",
      "count": 23345129,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "e6b7d6e9-8f84-4c87-b6c1-70f8f2217e40"
        }
      ]
    },
    {
      "source": "Europepmc.Target_disease_association",
      "target": "Disease",
      "label": "Has_object",
      "group": "Other",
      "count": 23343725,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "632f275a-060a-42f4-9656-0f05c4f6935b"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Disease",
      "label": "By_datasource_indirect.Has_summary_association",
      "group": "Aggregation",
      "count": 14133472,
      "properties": [
        {
          "property": "score",
          "type": "FLOAT",
          "example": 0.65181664641254
        },
        {
          "property": "evidenceCount",
          "type": "INTEGER",
          "example": 5
        },
        {
          "property": "datasourceId",
          "type": "STRING",
          "example": "europepmc"
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "3231feb4-1365-4f39-a9f9-c933ec2982b5"
        },
        {
          "property": "datatypeId",
          "type": "STRING",
          "example": "literature"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Disease",
      "label": "By_datatype_indirect.Has_summary_association",
      "group": "Aggregation",
      "count": 13814977,
      "properties": [
        {
          "property": "score",
          "type": "FLOAT",
          "example": 0.030396539880581056
        },
        {
          "property": "evidenceCount",
          "type": "INTEGER",
          "example": 1
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "3119b01d-7c4b-44bb-bfae-279f8984530f"
        },
        {
          "property": "datatypeId",
          "type": "STRING",
          "example": "literature"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Disease",
      "label": "By_overall_indirect.Has_summary_association",
      "group": "Aggregation",
      "count": 11951336,
      "properties": [
        {
          "property": "score",
          "type": "FLOAT",
          "example": 0.0036957985468470183
        },
        {
          "property": "evidenceCount",
          "type": "INTEGER",
          "example": 1
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "9aa9811e-8b38-4a12-99fd-c3b55ca9b2aa"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Disease",
      "label": "By_datasource_direct.Has_summary_association",
      "group": "Aggregation",
      "count": 4708628,
      "properties": [
        {
          "property": "score",
          "type": "FLOAT",
          "example": 0.27873120461494816
        },
        {
          "property": "evidenceCount",
          "type": "INTEGER",
          "example": 5
        },
        {
          "property": "datasourceId",
          "type": "STRING",
          "example": "europepmc"
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "4eb30fc9-f33f-40c9-9eda-51dbf1b10e6d"
        },
        {
          "property": "datatypeId",
          "type": "STRING",
          "example": "literature"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Disease",
      "label": "By_datatype_direct.Has_summary_association",
      "group": "Aggregation",
      "count": 4681972,
      "properties": [
        {
          "property": "score",
          "type": "FLOAT",
          "example": 0.2615368952224995
        },
        {
          "property": "evidenceCount",
          "type": "INTEGER",
          "example": 4
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "d7852c4c-33d1-4aca-b174-66002e58f9e1"
        },
        {
          "property": "datatypeId",
          "type": "STRING",
          "example": "literature"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Disease",
      "label": "By_overall_direct.Has_summary_association",
      "group": "Aggregation",
      "count": 4490041,
      "properties": [
        {
          "property": "score",
          "type": "FLOAT",
          "example": 0.03179926666349622
        },
        {
          "property": "evidenceCount",
          "type": "INTEGER",
          "example": 4
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "177ed3fa-8ff3-4341-a500-1e546b5206a1"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Biosample",
      "label": "Expressed_in",
      "group": "Experimental",
      "count": 4468214,
      "properties": [
        {
          "property": "rna_zscore",
          "type": "INTEGER",
          "example": -1
        },
        {
          "property": "rna_unit",
          "type": "STRING",
          "example": "TPM"
        },
        {
          "property": "rna_value",
          "type": "FLOAT",
          "example": 186.0
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "a0817e83-efd1-4acc-ad74-1a7695b819f8"
        },
        {
          "property": "label",
          "type": "STRING",
          "example": "lung"
        },
        {
          "property": "protein_level",
          "type": "INTEGER",
          "example": 2
        },
        {
          "property": "protein_reliability",
          "type": "BOOLEAN",
          "example": false
        },
        {
          "property": "rna_level",
          "type": "INTEGER",
          "example": 2
        }
      ]
    },
    {
      "source": "Target",
      "target": "Species",
      "label": "Has_homologue_in_species",
      "group": "Relation",
      "count": 3817509,
      "properties": [
        {
          "property": "isHighConfidence",
          "type": "STRING",
          "example": "NULL"
        },
        {
          "property": "queryPercentageIdentity",
          "type": "FLOAT",
          "example": 21.8023
        },
        {
          "property": "homologyType",
          "type": "STRING",
          "example": "other_paralog"
        },
        {
          "property": "targetGeneId",
          "type": "STRING",
          "example": "ENSG00000142186"
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "5759ec70-8908-42e6-970d-a914225f14bd"
        },
        {
          "property": "targetPercentageIdentity",
          "type": "FLOAT",
          "example": 18.5644
        },
        {
          "property": "priority",
          "type": "INTEGER",
          "example": 0
        },
        {
          "property": "targetGeneSymbol",
          "type": "STRING",
          "example": "SCYL1"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Eva.Target_disease_association",
      "label": "Subject_of",
      "group": "Other",
      "count": 3535067,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "e6b7d6e9-8f84-4c87-b6c1-70f8f2217e40"
        }
      ]
    },
    {
      "source": "Eva.Target_disease_association",
      "target": "Disease",
      "label": "Has_object",
      "group": "Other",
      "count": 3535067,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "632f275a-060a-42f4-9656-0f05c4f6935b"
        }
      ]
    },
    {
      "source": "Genetic_association_study",
      "target": "Credible_set",
      "label": "Has_credible_set",
      "group": "Relation",
      "count": 3484825,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "331def67-459f-4275-ba9d-cdcb73681646"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Gwas_credible_sets.Target_disease_association",
      "label": "Subject_of",
      "group": "Other",
      "count": 2976160,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "e6b7d6e9-8f84-4c87-b6c1-70f8f2217e40"
        }
      ]
    },
    {
      "source": "Gwas_credible_sets.Target_disease_association",
      "target": "Disease",
      "label": "Has_object",
      "group": "Other",
      "count": 2973959,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "632f275a-060a-42f4-9656-0f05c4f6935b"
        }
      ]
    },
    {
      "source": "Credible_set",
      "target": "Target",
      "label": "Predicts_target",
      "group": "Experimental",
      "count": 2854486,
      "properties": [
        {
          "property": "score",
          "type": "FLOAT",
          "example": 0.9387354850769043
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "58988cba-d325-48bc-89cf-d357dd4ab2cc"
        }
      ]
    },
    {
      "source": "Genetic_association_study",
      "target": "Target",
      "label": "Reports_trait",
      "group": "Other",
      "count": 1865583,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "dc9be824-aa4c-4b97-8f1b-04870ee3a0b4"
        }
      ]
    },
    {
      "source": "Genetic_association_study",
      "target": "Biosample",
      "label": "Measured_in",
      "group": "Experimental",
      "count": 1865583,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "2b773740-c600-4248-a5fe-33dcd811c0f4"
        }
      ]
    },
    {
      "source": "Target_target_interaction",
      "target": "Literature_entry",
      "label": "Supported_by",
      "group": "Other",
      "count": 1813302,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "f532fb4b-7ca4-42fc-8470-dd9fa97a020c"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Impc.Target_disease_association",
      "label": "Subject_of",
      "group": "Other",
      "count": 1563525,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "e6b7d6e9-8f84-4c87-b6c1-70f8f2217e40"
        }
      ]
    },
    {
      "source": "Impc.Target_disease_association",
      "target": "Disease",
      "label": "Has_object",
      "group": "Other",
      "count": 1563525,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "632f275a-060a-42f4-9656-0f05c4f6935b"
        }
      ]
    },
    {
      "source": "Genetic_association_study",
      "target": "Literature_entry",
      "label": "Published_in",
      "group": "Other",
      "count": 756664,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "67fd169f-c848-4ca0-aedd-a65e490a6ec6"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Go_term",
      "label": "Related_to",
      "group": "Other",
      "count": 755793,
      "properties": [
        {
          "property": "ecoId",
          "type": "STRING",
          "example": "ECO:0000265"
        },
        {
          "property": "evidence",
          "type": "STRING",
          "example": ""
        },
        {
          "property": "geneProduct",
          "type": "STRING",
          "example": "Q8IZE3"
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "6a264c01-c0bf-469f-9690-9ce15d075e8f"
        },
        {
          "property": "source",
          "type": "STRING",
          "example": "GO_REF:0000107"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Chembl.Target_disease_association",
      "label": "Subject_of",
      "group": "Other",
      "count": 569506,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "e6b7d6e9-8f84-4c87-b6c1-70f8f2217e40"
        }
      ]
    },
    {
      "source": "Chembl.Target_disease_association",
      "target": "Disease",
      "label": "Has_object",
      "group": "Other",
      "count": 569481,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "632f275a-060a-42f4-9656-0f05c4f6935b"
        }
      ]
    },
    {
      "source": "Chembl.Target_disease_association",
      "target": "Molecule",
      "label": "Has_molecule",
      "group": "Relation",
      "count": 568603,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "20c910f9-7b3a-499f-a803-6c12526d0289"
        }
      ]
    },
    {
      "source": "Mouse_phenotype",
      "target": "Mouse_phenotype",
      "label": "Classified_as",
      "group": "Hierarchy",
      "count": 241580,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "e2e1b7d2-7973-47a5-a94b-606fbba55ea4"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Expression_atlas.Target_disease_association",
      "label": "Subject_of",
      "group": "Other",
      "count": 237329,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "e6b7d6e9-8f84-4c87-b6c1-70f8f2217e40"
        }
      ]
    },
    {
      "source": "Expression_atlas.Target_disease_association",
      "target": "Disease",
      "label": "Has_object",
      "group": "Other",
      "count": 237329,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "632f275a-060a-42f4-9656-0f05c4f6935b"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Mouse_gene",
      "label": "Modelled_by",
      "group": "Experimental",
      "count": 210569,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "8cbbf6de-d1df-4a90-97a7-ca8897cb45a7"
        }
      ]
    },
    {
      "source": "Disease",
      "target": "Disease_phenotype_association",
      "label": "Subject_of",
      "group": "Other",
      "count": 208450,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "e6b7d6e9-8f84-4c87-b6c1-70f8f2217e40"
        }
      ]
    },
    {
      "source": "Genetic_association_study",
      "target": "Disease",
      "label": "Reports_trait",
      "group": "Other",
      "count": 144867,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "dc9be824-aa4c-4b97-8f1b-04870ee3a0b4"
        }
      ]
    },
    {
      "source": "Disease_phenotype_association",
      "target": "Disease",
      "label": "Has_object",
      "group": "Other",
      "count": 136170,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "632f275a-060a-42f4-9656-0f05c4f6935b"
        }
      ]
    },
    {
      "source": "Disease",
      "target": "Database_cross_reference",
      "label": "Has_database_cross_reference",
      "group": "Relation",
      "count": 134165,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "66c31bba-987f-4227-a04a-d0f9c4c7547f"
        }
      ]
    },
    {
      "source": "Disease",
      "target": "Disease_synonym",
      "label": "Has_synonym",
      "group": "Relation",
      "count": 121532,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "9848003b-a3ce-42f7-ad77-757b4595a159"
        }
      ]
    },
    {
      "source": "Molecule",
      "target": "Adverse_reaction",
      "label": "Has_adverse_reaction",
      "group": "Relation",
      "count": 114503,
      "properties": [
        {
          "property": "llr",
          "type": "FLOAT",
          "example": 145.83109388945013
        },
        {
          "property": "count",
          "type": "INTEGER",
          "example": 78
        },
        {
          "property": "critval",
          "type": "FLOAT",
          "example": 68.37869336787405
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "544b9213-8b91-49a1-865a-ab1ca5e041d7"
        },
        {
          "property": "event",
          "type": "STRING",
          "example": "acute generalised exanthematous pustulosis"
        },
        {
          "property": "meddraCode",
          "type": "STRING",
          "example": "10048799"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Cancer_gene_census.Target_disease_association",
      "label": "Subject_of",
      "group": "Other",
      "count": 91572,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "e6b7d6e9-8f84-4c87-b6c1-70f8f2217e40"
        }
      ]
    },
    {
      "source": "Cancer_gene_census.Target_disease_association",
      "target": "Disease",
      "label": "Has_object",
      "group": "Other",
      "count": 91572,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "632f275a-060a-42f4-9656-0f05c4f6935b"
        }
      ]
    },
    {
      "source": "Biosample",
      "target": "Biosample",
      "label": "Is_a",
      "group": "Hierarchy",
      "count": 80274,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "c7896f16-ac35-425c-a9d5-5d7de7e0d653"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Target_prioritisation",
      "label": "Has_prioritisation",
      "group": "Relation",
      "count": 78725,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "10a828f5-6a47-4202-b30b-6a36a9a68fbe"
        }
      ]
    },
    {
      "source": "Disease_phenotype_association",
      "target": "Phenotype",
      "label": "Has_object",
      "group": "Other",
      "count": 72247,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "632f275a-060a-42f4-9656-0f05c4f6935b"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Biosample",
      "label": "By_datasource_indirect.Has_summary_association",
      "group": "Aggregation",
      "count": 71705,
      "properties": [
        {
          "property": "score",
          "type": "FLOAT",
          "example": 0.65181664641254
        },
        {
          "property": "evidenceCount",
          "type": "INTEGER",
          "example": 5
        },
        {
          "property": "datasourceId",
          "type": "STRING",
          "example": "europepmc"
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "3231feb4-1365-4f39-a9f9-c933ec2982b5"
        },
        {
          "property": "datatypeId",
          "type": "STRING",
          "example": "literature"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Biosample",
      "label": "By_datatype_indirect.Has_summary_association",
      "group": "Aggregation",
      "count": 71273,
      "properties": [
        {
          "property": "score",
          "type": "FLOAT",
          "example": 0.030396539880581056
        },
        {
          "property": "evidenceCount",
          "type": "INTEGER",
          "example": 1
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "3119b01d-7c4b-44bb-bfae-279f8984530f"
        },
        {
          "property": "datatypeId",
          "type": "STRING",
          "example": "literature"
        }
      ]
    },
    {
      "source": "Molecule",
      "target": "Disease",
      "label": "Indicates",
      "group": "Other",
      "count": 66486,
      "properties": [
        {
          "property": "maxPhaseForIndication",
          "type": "FLOAT",
          "example": 2.0
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "49c631bf-7e02-44be-8d7e-1f4de2b33197"
        }
      ]
    },
    {
      "source": "Disease",
      "target": "Disease",
      "label": "Is_a",
      "group": "Hierarchy",
      "count": 64680,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "c7896f16-ac35-425c-a9d5-5d7de7e0d653"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Biosample",
      "label": "By_overall_indirect.Has_summary_association",
      "group": "Aggregation",
      "count": 59424,
      "properties": [
        {
          "property": "score",
          "type": "FLOAT",
          "example": 0.0036957985468470183
        },
        {
          "property": "evidenceCount",
          "type": "INTEGER",
          "example": 1
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "9aa9811e-8b38-4a12-99fd-c3b55ca9b2aa"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Subcellular_location",
      "label": "Located_in",
      "group": "Hierarchy",
      "count": 57685,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "9ba0ad48-8779-4303-951a-74feaecb18ae"
        },
        {
          "property": "source",
          "type": "STRING",
          "example": "uniprot"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Genomics_england.Target_disease_association",
      "label": "Subject_of",
      "group": "Other",
      "count": 48545,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "e6b7d6e9-8f84-4c87-b6c1-70f8f2217e40"
        }
      ]
    },
    {
      "source": "Genomics_england.Target_disease_association",
      "target": "Disease",
      "label": "Has_object",
      "group": "Other",
      "count": 48545,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "632f275a-060a-42f4-9656-0f05c4f6935b"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Pathway",
      "label": "Involves_in",
      "group": "Hierarchy",
      "count": 48176,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "1ed2ae36-4f95-4b9d-b0f6-2606afc981bf"
        }
      ]
    },
    {
      "source": "Mouse_phenotype",
      "target": "Mouse_phenotype_class",
      "label": "Classified_as",
      "group": "Hierarchy",
      "count": 42588,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "e2e1b7d2-7973-47a5-a94b-606fbba55ea4"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Gene_burden.Target_disease_association",
      "label": "Subject_of",
      "group": "Other",
      "count": 41264,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "e6b7d6e9-8f84-4c87-b6c1-70f8f2217e40"
        }
      ]
    },
    {
      "source": "Gene_burden.Target_disease_association",
      "target": "Disease",
      "label": "Has_object",
      "group": "Other",
      "count": 41257,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "632f275a-060a-42f4-9656-0f05c4f6935b"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Uniprot_variants.Target_disease_association",
      "label": "Subject_of",
      "group": "Other",
      "count": 36870,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "e6b7d6e9-8f84-4c87-b6c1-70f8f2217e40"
        }
      ]
    },
    {
      "source": "Uniprot_variants.Target_disease_association",
      "target": "Disease",
      "label": "Has_object",
      "group": "Other",
      "count": 36870,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "632f275a-060a-42f4-9656-0f05c4f6935b"
        }
      ]
    },
    {
      "source": "Pharmacogenomics_annotation",
      "target": "Molecule",
      "label": "Has_molecule",
      "group": "Relation",
      "count": 28623,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "20c910f9-7b3a-499f-a803-6c12526d0289"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Adverse_reaction",
      "label": "Associated_with",
      "group": "Other",
      "count": 28382,
      "properties": [
        {
          "property": "llr",
          "type": "FLOAT",
          "example": 187.39907561057043
        },
        {
          "property": "count",
          "type": "INTEGER",
          "example": 249
        },
        {
          "property": "critval",
          "type": "FLOAT",
          "example": 120.005902881152
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "71069f32-6080-44f3-bd78-61bf2002f1be"
        },
        {
          "property": "event",
          "type": "STRING",
          "example": "alanine aminotransferase increased"
        },
        {
          "property": "meddraCode",
          "type": "STRING",
          "example": "10001551"
        }
      ]
    },
    {
      "source": "Pharmacogenomics_annotation",
      "target": "Target",
      "label": "Has_target",
      "group": "Relation",
      "count": 24821,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "5a92a5b0-d1a7-4c15-9f79-5bf002d357af"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Crispr_screen.Target_disease_association",
      "label": "Subject_of",
      "group": "Other",
      "count": 21681,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "e6b7d6e9-8f84-4c87-b6c1-70f8f2217e40"
        }
      ]
    },
    {
      "source": "Crispr_screen.Target_disease_association",
      "target": "Disease",
      "label": "Has_object",
      "group": "Other",
      "count": 21681,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "632f275a-060a-42f4-9656-0f05c4f6935b"
        }
      ]
    },
    {
      "source": "Cell_line",
      "target": "Biosample",
      "label": "Sampled_from",
      "group": "Experimental",
      "count": 18556,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "76a5126f-428d-4ded-88fa-9d5ed35464e1"
        }
      ]
    },
    {
      "source": "Crispr.Target_disease_association",
      "target": "Cell_line",
      "label": "Tested_in",
      "group": "Experimental",
      "count": 18556,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "daa5ad06-4ee2-4c1c-927b-6082fc8bb653"
        }
      ]
    },
    {
      "source": "Phenotype",
      "target": "Phenotype",
      "label": "Is_a",
      "group": "Hierarchy",
      "count": 17993,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "c7896f16-ac35-425c-a9d5-5d7de7e0d653"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Target_classification",
      "label": "Belongs_to",
      "group": "Hierarchy",
      "count": 15999,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "1ceb37d1-349f-4dc1-b586-2e43364c9122"
        }
      ]
    },
    {
      "source": "Pharmacogenomics_annotation",
      "target": "Variant",
      "label": "Has_variant",
      "group": "Relation",
      "count": 15886,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "4368fd6a-ba81-4a91-be8f-2ab08716edef"
        }
      ]
    },
    {
      "source": "Mechanism_of_action",
      "target": "Target",
      "label": "Has_target",
      "group": "Relation",
      "count": 12703,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "5a92a5b0-d1a7-4c15-9f79-5bf002d357af"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Reactome.Target_disease_association",
      "label": "Subject_of",
      "group": "Other",
      "count": 10211,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "e6b7d6e9-8f84-4c87-b6c1-70f8f2217e40"
        }
      ]
    },
    {
      "source": "Reactome.Target_disease_association",
      "target": "Disease",
      "label": "Has_object",
      "group": "Other",
      "count": 10211,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "632f275a-060a-42f4-9656-0f05c4f6935b"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Eva_somatic.Target_disease_association",
      "label": "Subject_of",
      "group": "Other",
      "count": 9342,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "e6b7d6e9-8f84-4c87-b6c1-70f8f2217e40"
        }
      ]
    },
    {
      "source": "Eva_somatic.Target_disease_association",
      "target": "Disease",
      "label": "Has_object",
      "group": "Other",
      "count": 9342,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "632f275a-060a-42f4-9656-0f05c4f6935b"
        }
      ]
    },
    {
      "source": "Molecule",
      "target": "Mechanism_of_action",
      "label": "Has_mechanism_of_action",
      "group": "Relation",
      "count": 7921,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "324b278a-229a-4a7a-8e54-7414e8f94429"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Orphanet.Target_disease_association",
      "label": "Subject_of",
      "group": "Other",
      "count": 7189,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "e6b7d6e9-8f84-4c87-b6c1-70f8f2217e40"
        }
      ]
    },
    {
      "source": "Orphanet.Target_disease_association",
      "target": "Disease",
      "label": "Has_object",
      "group": "Other",
      "count": 7189,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "632f275a-060a-42f4-9656-0f05c4f6935b"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Uniprot_literature.Target_disease_association",
      "label": "Subject_of",
      "group": "Other",
      "count": 6735,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "e6b7d6e9-8f84-4c87-b6c1-70f8f2217e40"
        }
      ]
    },
    {
      "source": "Uniprot_literature.Target_disease_association",
      "target": "Disease",
      "label": "Has_object",
      "group": "Other",
      "count": 6735,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "632f275a-060a-42f4-9656-0f05c4f6935b"
        }
      ]
    },
    {
      "source": "Pathway",
      "target": "Disease",
      "label": "Annotated_with",
      "group": "Other",
      "count": 6587,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "bebe9949-2aa9-4fe8-b335-f325c0fe70b7"
        }
      ]
    },
    {
      "source": "Pathway",
      "target": "Pathway",
      "label": "Is_part_of",
      "group": "Hierarchy",
      "count": 5682,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "5170bfcc-4153-4092-9e01-2bd337c683c3"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Gene2phenotype.Target_disease_association",
      "label": "Subject_of",
      "group": "Other",
      "count": 5062,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "e6b7d6e9-8f84-4c87-b6c1-70f8f2217e40"
        }
      ]
    },
    {
      "source": "Gene2phenotype.Target_disease_association",
      "target": "Disease",
      "label": "Has_object",
      "group": "Other",
      "count": 5062,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "632f275a-060a-42f4-9656-0f05c4f6935b"
        }
      ]
    },
    {
      "source": "Phenotype",
      "target": "Disease",
      "label": "Is_a",
      "group": "Hierarchy",
      "count": 4983,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "c7896f16-ac35-425c-a9d5-5d7de7e0d653"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Intogen.Target_disease_association",
      "label": "Subject_of",
      "group": "Other",
      "count": 4223,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "e6b7d6e9-8f84-4c87-b6c1-70f8f2217e40"
        }
      ]
    },
    {
      "source": "Intogen.Target_disease_association",
      "target": "Disease",
      "label": "Has_object",
      "group": "Other",
      "count": 4223,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "632f275a-060a-42f4-9656-0f05c4f6935b"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Clingen.Target_disease_association",
      "label": "Subject_of",
      "group": "Other",
      "count": 3904,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "e6b7d6e9-8f84-4c87-b6c1-70f8f2217e40"
        }
      ]
    },
    {
      "source": "Clingen.Target_disease_association",
      "target": "Disease",
      "label": "Has_object",
      "group": "Other",
      "count": 3904,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "632f275a-060a-42f4-9656-0f05c4f6935b"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Biosample",
      "label": "By_datasource_direct.Has_summary_association",
      "group": "Aggregation",
      "count": 2936,
      "properties": [
        {
          "property": "score",
          "type": "FLOAT",
          "example": 0.27873120461494816
        },
        {
          "property": "evidenceCount",
          "type": "INTEGER",
          "example": 5
        },
        {
          "property": "datasourceId",
          "type": "STRING",
          "example": "europepmc"
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "4eb30fc9-f33f-40c9-9eda-51dbf1b10e6d"
        },
        {
          "property": "datatypeId",
          "type": "STRING",
          "example": "literature"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Biosample",
      "label": "By_datatype_direct.Has_summary_association",
      "group": "Aggregation",
      "count": 2935,
      "properties": [
        {
          "property": "score",
          "type": "FLOAT",
          "example": 0.2615368952224995
        },
        {
          "property": "evidenceCount",
          "type": "INTEGER",
          "example": 4
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "d7852c4c-33d1-4aca-b174-66002e58f9e1"
        },
        {
          "property": "datatypeId",
          "type": "STRING",
          "example": "literature"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Biosample",
      "label": "By_overall_direct.Has_summary_association",
      "group": "Aggregation",
      "count": 2930,
      "properties": [
        {
          "property": "score",
          "type": "FLOAT",
          "example": 0.03179926666349622
        },
        {
          "property": "evidenceCount",
          "type": "INTEGER",
          "example": 4
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "177ed3fa-8ff3-4341-a500-1e546b5206a1"
        }
      ]
    },
    {
      "source": "Molecule",
      "target": "Drug_warning",
      "label": "Has_drug_warning",
      "group": "Relation",
      "count": 2892,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "e9e47633-601d-46ba-a69a-e9e922b23c49"
        }
      ]
    },
    {
      "source": "Gwas_credible_sets.Target_disease_association",
      "target": "Biosample",
      "label": "Has_object",
      "group": "Other",
      "count": 2201,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "632f275a-060a-42f4-9656-0f05c4f6935b"
        }
      ]
    },
    {
      "source": "Molecule",
      "target": "Molecule",
      "label": "Derived_from",
      "group": "Other",
      "count": 1684,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "d8c1ae74-a403-495a-b5a0-6f712e436601"
        }
      ]
    },
    {
      "source": "Disease",
      "target": "Phenotype",
      "label": "Is_a",
      "group": "Hierarchy",
      "count": 1584,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "c7896f16-ac35-425c-a9d5-5d7de7e0d653"
        }
      ]
    },
    {
      "source": "Europepmc.Target_disease_association",
      "target": "Biosample",
      "label": "Has_object",
      "group": "Other",
      "count": 1404,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "632f275a-060a-42f4-9656-0f05c4f6935b"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Cancer_biomarkers.Target_disease_association",
      "label": "Subject_of",
      "group": "Other",
      "count": 1301,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "e6b7d6e9-8f84-4c87-b6c1-70f8f2217e40"
        }
      ]
    },
    {
      "source": "Cancer_biomarkers.Target_disease_association",
      "target": "Disease",
      "label": "Has_object",
      "group": "Other",
      "count": 1301,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "632f275a-060a-42f4-9656-0f05c4f6935b"
        }
      ]
    },
    {
      "source": "Phenotype",
      "target": "Biosample",
      "label": "Is_a",
      "group": "Hierarchy",
      "count": 1244,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "c7896f16-ac35-425c-a9d5-5d7de7e0d653"
        }
      ]
    },
    {
      "source": "Cancer_biomarkers.Target_disease_association",
      "target": "Molecule",
      "label": "Has_molecule",
      "group": "Relation",
      "count": 728,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "20c910f9-7b3a-499f-a803-6c12526d0289"
        }
      ]
    },
    {
      "source": "Biosample",
      "target": "Disease_synonym",
      "label": "Has_synonym",
      "group": "Relation",
      "count": 612,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "9848003b-a3ce-42f7-ad77-757b4595a159"
        }
      ]
    },
    {
      "source": "Target",
      "target": "Crispr.Target_disease_association",
      "label": "Subject_of",
      "group": "Other",
      "count": 517,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "e6b7d6e9-8f84-4c87-b6c1-70f8f2217e40"
        }
      ]
    },
    {
      "source": "Crispr.Target_disease_association",
      "target": "Disease",
      "label": "Has_object",
      "group": "Other",
      "count": 517,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "632f275a-060a-42f4-9656-0f05c4f6935b"
        }
      ]
    },
    {
      "source": "Disease",
      "target": "Biosample",
      "label": "Is_a",
      "group": "Hierarchy",
      "count": 445,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "c7896f16-ac35-425c-a9d5-5d7de7e0d653"
        }
      ]
    },
    {
      "source": "Genetic_association_study",
      "target": "Biosample",
      "label": "Reports_trait",
      "group": "Other",
      "count": 358,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "dc9be824-aa4c-4b97-8f1b-04870ee3a0b4"
        }
      ]
    },
    {
      "source": "Biosample",
      "target": "Database_cross_reference",
      "label": "Has_database_cross_reference",
      "group": "Relation",
      "count": 327,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "66c31bba-987f-4227-a04a-d0f9c4c7547f"
        }
      ]
    },
    {
      "source": "Cancer_biomarkers.Target_disease_association",
      "target": "Disease",
      "label": "Has_drug_response",
      "group": "Relation",
      "count": 302,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "135018ff-7559-4c15-82a8-d27160fd47cb"
        }
      ]
    },
    {
      "source": "Chembl.Target_disease_association",
      "target": "Biosample",
      "label": "Has_object",
      "group": "Other",
      "count": 25,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "632f275a-060a-42f4-9656-0f05c4f6935b"
        }
      ]
    },
    {
      "source": "Molecule",
      "target": "Biosample",
      "label": "Indicates",
      "group": "Other",
      "count": 12,
      "properties": [
        {
          "property": "maxPhaseForIndication",
          "type": "FLOAT",
          "example": 2.0
        },
        {
          "property": "id",
          "type": "STRING",
          "example": "49c631bf-7e02-44be-8d7e-1f4de2b33197"
        }
      ]
    },
    {
      "source": "Biosample",
      "target": "Disease",
      "label": "Is_a",
      "group": "Hierarchy",
      "count": 11,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "c7896f16-ac35-425c-a9d5-5d7de7e0d653"
        }
      ]
    },
    {
      "source": "Biosample",
      "target": "Phenotype",
      "label": "Is_a",
      "group": "Hierarchy",
      "count": 11,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "c7896f16-ac35-425c-a9d5-5d7de7e0d653"
        }
      ]
    },
    {
      "source": "Gene_burden.Target_disease_association",
      "target": "Biosample",
      "label": "Has_object",
      "group": "Other",
      "count": 7,
      "properties": [
        {
          "property": "id",
          "type": "STRING",
          "example": "632f275a-060a-42f4-9656-0f05c4f6935b"
        }
      ]
    }
  ]
}